Quantum Genomics

We develop quantum algorithms and quantum-inspired methods to solve the hardest computational problems in genomics.

  • Result The complete hepatitis delta virus genome loaded onto quantum hardware, with the University of Melbourne. Publication in preparation. Coverage →
  • Hardware Methods validated on IBM, Quantinuum and IonQ devices. How we validate →
  • Team A team based in Oxford, Cambridge and Kyiv. Who we are →
  • Open research Check our publications. Publications →

Research

Research strands

  • Pangenome-guided sequence assembly

    Genome assembly reformulated as graph-traversal optimisation and solved with iterative QAOA.

  • Phylogeny

    Hybrid quantum and classical pre-processing with a QAOA solver for the maximum weighted clique problem.

  • MPS-based genome encoding

    Exact, information-conserving encoding of whole genomes as quantum states.

  • ML-based DNA encoding

    A correlation-preserving encoding of DNA, and RotorMap for mapping long, noisy reads.

Result

A complete genome on quantum hardware

The complete hepatitis delta virus genome, 1,614 bases, has been encoded and loaded onto NISQ hardware as a single quantum state, in collaboration with the University of Melbourne. It is the first time a whole genome has been loaded onto a quantum computer, and at least an order of magnitude larger than previous attempts. Publication in preparation.

See the coverage →

People

Founders

  • Dr Sergii Strelchuk Co-founder and Chief Scientific Officer

    Dr Sergii Strelchuk

    Associate Professor, University of Oxford

    Led the Quantum Pangenomics team that achieved the first loading of a complete genome onto a quantum computer.

  • Dr James McCafferty Co-founder and Adviser

    Dr James McCafferty

    Former Chief Information Officer, Wellcome Sanger Institute

    Over thirty years of experience in IT systems, bioinformatics and digital transformation.

Team

  • Dr Danylo Yakymenko Kyiv Academic University
  • Dr Alina Frolova Institute of Molecular Biology and Genetics, Kyiv
  • Orson Ye University of Cambridge

Advisers

  • Professor Richard Durbin FRS Professor of Genetics, University of Cambridge

Team →

Contact

info@q4genomics.com

Cambridge, United Kingdom · LinkedIn · X